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Updated: Jul 16, 2026

Multiplexed Single-molecule Force Proteolysis Measurements Using Magnetic Tweezers
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用单分子磁性笔对人类XPD酶活性进行表征

Chunfeng Mao1, Maria Mills1

  • 1Department of Physics and Astronomy, University of Missouri, Columbia, Missouri.

Biophysical journal
|December 19, 2023
PubMed
概括

人类XPD螺旋酶缓慢地解开DNA,过程性较低. 它的解和转移率相似,这表明转移决定了整体活动.

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相关概念视频

DNA Helicases00:55

DNA Helicases

DNA unwinding helicase enzymes are a type of motor protein. Motor proteins can translocate along filaments or polymers using energy generated from ATP hydrolysis. Helicases are involved in all the important cellular processes where DNA unwinding is required, such as DNA replication, repair, recombination, and transcription. They are present in all living organisms, but vary in their structure, function, and mechanism of action. For example, in prokaryotes, DnaB helicase binds and translocates...