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Updated: Jul 8, 2025

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在老化蛋白质组中的三氧化氨酸模仿了酸化氨酸的结构动态和相互作用

Jose Antonio Sánchez Milán1,2, María Fernández-Rhodes1,2, Xue Guo3

  • 1Biomedical Research Institute of Lleida (IRBLLEIDA) - +Pec Proteomics Research Group (+PPRG) - Neuroscience Area, University Hospital Arnau de Vilanova (HUAV), Lleida, Spain.

Aging cell
|December 19, 2023
PubMed
概括

衰老加速蛋白质损伤,三氧化氨酸 (t-Cys) 积累并影响细胞信号,类似于异常的血清酸化 (p-Ser). 这揭示了氧化应激和老化中的酸化之间的关键相互作用.

关键词:
老化的老化 衰老的老化生物信息学是一种生物信息学.退行性蛋白质修饰 退行性蛋白质修饰激酶激酶是一种激素.分子动力学分子动力学酸化的方法是:光化.翻译后的修改 翻译后的修改蛋白质结构 蛋白质结构蛋白质组是一种蛋白质组.信号传输 信号传输硫醇三氧化半氨酸氨酸.

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