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Updated: Jul 8, 2025

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
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基于MALDI-TOF MS和机器学习的Bifidobacterium longum亚种的快速歧视

Kexin Liu1,2, Yajie Wang3, Minlei Zhao4

  • 1College of Life Science, North China University of Science and Technology, Tangshan, China.

Frontiers in microbiology
|December 19, 2023
PubMed
概括

矩阵辅助激光脱/离子化飞行时间质谱学 (MALDI-TOF MS) 结合机器学习准确区分Bifidobacterium longum亚种infantis和longum. 这种方法为益生菌和药品提供了快速而精确的亚种识别.

关键词:
B. 婴儿科 婴儿科B.长长 (英语:longum) 是指一个长.这是一种Bifidobacterium longum亚种.马尔迪-托夫 (MALDI-TOF) 是一个国家元首.标识 标识 标识 标识 标识机器学习是机器学习.

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相关概念视频

MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.
Matrix-assisted laser desorption ionization (MALDI) is a commonly...
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Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
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Matrix-Assisted Laser Desorption Ionization (MALDI)01:08

Matrix-Assisted Laser Desorption Ionization (MALDI)

Matrix-assisted laser desorption ionization (MALDI) is a powerful analytical technique used in mass spectrometry. It enables the identification and characterization of various biomolecules, including proteins, peptides, nucleic acids, and carbohydrates. MALDI spectrometry is widely employed in biological and medical research, as well as in fields like pharmacology and biochemistry.
The analyte of interest, a biomolecule or a mixture of biomolecules, is mixed with a suitable matrix material. The...
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