评估多站点编程包,以减少对呼吸道感染的不必要的抗生素处方:一个回顾性队列研究
Dan Ilges1, Kelsey Jensen2, Evan Draper3
1Department of Pharmacy Services, Mayo Clinic Arizona, Phoenix, Arizona, USA.
抗微生物管理干预显著减少了对上呼吸道感染 (URI) 不必要的抗生素处方. 这一举措降低了处方率,而不增加重复的医疗保健访问,突出了其优化抗生素使用的有效性.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 对上呼吸道感染 (URIs) 不必要的抗生素处方仍然是一个重大挑战.
- 评估抗微生物药物管理干预措施对于优化门诊环境中的抗生素使用至关重要.
研究的目的:
- 评估多方面的抗微生物管理干预对抗生素处方对Tier 3 URI综合征的影响.
- 为了确定与抗生素处方相关的因素,并在干预后重复呼吸系统医疗保健联系.
主要方法:
- 从2019年1月到2022年12月进行了一项准实验性,前/后回顾性队列研究.
- 包括为Tier 3 URI诊断的门诊接触,包括初级保健,紧急护理和紧急医疗.
- 该干预涉及一个多方面的门诊抗生素管理包.
主要成果:
- 针对Tier 3 URI的抗生素处方从干预前的21.7%下降到干预后的11.2% (P < .001).
- 在没有抗生素的小组中,干预后14天的呼吸卫生保健重复接触率较低 (9.4% vs 9.9%,P = .004).
- 增加患者年龄,并发症指数和初级诊断与持续不必要的处方有关.
结论:
- 门诊抗生素管理计划有效地减少了对URI的不必要的抗生素处方.
- 这些举措并没有增加呼吸系统医疗保健的重复接触.
- 患者的年龄和并发症是持续不必要的抗生素处方的关键风险因素.
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