在西班牙裔人群中,口腔炎和人类乳头瘤病毒协会
Maira A Castañeda-Avila1, Cynthia M Pérez2, José Vivaldi3
1Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
International journal of dentistry
|December 19, 2023
概括
牙和牙周炎症与成人口腔人类乳头瘤病毒 (HPV) 感染有关. 这种联系突出了减少与HPV相关的癌症的潜在新策略.
科学领域:
- 口腔健康研究 口腔健康研究
- 传染病流行病学 传染病流行病学
背景情况:
- 持续的人类乳头瘤病毒 (HPV) 感染是HPV相关癌症的关键因素.
- 了解与HPV感染相关的因素对于预防策略至关重要.
研究的目的:
- 调查牙/牙周炎症和口腔HPV感染之间的关联.
- 评估口腔炎作为口腔HPV的潜在风险因素.
主要方法:
- 在波多黎各对740名超重/肥胖成年人 (40-65岁) 的横截面研究.
- 用于检测HPV的口腔冲洗样品,包括在探针上出血 (BOP) 和探针口袋深度 (PPD) 在内的牙科检查.
- 多变量逻辑回归分析,以评估口腔炎症和口腔HPV之间的关联.
主要成果:
- 与没有HPV的参与者相比,患有口腔HPV的参与者平均BOP和PPD部位 (≥4mm) 显著更高.
- 增加口腔HPV感染的几率与较多的BOP部位 (3%) 和具有BOP部位的PPD (≥4mm) 部位 (5%) 相关.
- 在调整了性别,年龄,收入和口交伴侣后,关联仍然很重要.
结论:
- 在这个成年人群中,口腔炎与口腔HPV感染有显著的关联.
- 研究结果表明,牙周健康和HPV持久性之间存在潜在联系.
- 需要进一步的研究来阐明潜在的生物机制.
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