诺莫图谱用于预测远端胃切除术后的早期并发症
Biao Zhang1, Qing Zhu1, Zhi-Peng Ji2
1Department of Gastrointestinal Surgery, Second Hospital of Shandong University, Jinan 250033, Shandong Province, China.
World journal of gastrointestinal surgery
|December 19, 2023
概括
这项研究确定了胃癌 (GC) 远部胃切除术后早期术后并发症的关键风险因素. 一个经过验证的nomogram预测模型可以帮助针对高风险患者进行干预,减少并发症.
科学领域:
- 在瘤学瘤学.
- 外科胃肠道外科手术
- 医疗信息学 医疗信息学
背景情况:
- 胃癌 (GC) 患者的术后发病率是术后护理的一个关键问题.
- 尽量减少GC手术后的并发症对于患者的康复和治疗成功至关重要.
研究的目的:
- 为了确定GC的远端胃切除术后早期术后并发症的独立风险因素.
- 开发和验证这些并发症的预测性名ogram模型.
主要方法:
- 对131名经过远端胃切除术的GC患者进行了回顾性分析.
- 单变量和多变量逻辑回归用于识别风险因素.
- 使用内部和外部数据集 (n=45) 构建和验证名图.
- 接收器操作特征 (ROC) 曲线和决策曲线分析 (DCA) 用于模型评估.
主要成果:
- 高血压,糖尿病,先前的腹部手术和术前输血被确定为并发症的独立预测因素.
- 诺米图表表现出良好的预测性能,曲线下的面积 (AUC) 为0.843 (建模) 和0.877 (验证).
- 该模型显示高灵敏度 (0.762-0.778) 和特异性 (0.809-0.944),与良好的校准和临床实用性.
结论:
- 一个基于已识别的风险因素的诺姆图有效地预测了GC远端胃切除术后的术后并发症.
- 这种工具可以帮助高风险患者群体的术后干预策略.
- 实施名图可能会降低GC患者手术后并发症的发生率.
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