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磁纳米粒子介导的血栓溶解-一篇评论

Bohua Zhang¹, Xiaoning Jiang¹

¹Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695 USA.

IEEE open journal of nanotechnology

|December 19, 2023

概括

磁纳米颗粒为血栓形成提供有针对性的血栓溶解. 本综述探讨了它们在体外和体内使用的方法,包括带有声场的双模式方法,以增强凝块溶解.

科学领域:

生物医学工程生物医学工程
纳米技术纳米技术
心血管研究研究心血管研究

背景情况:

血栓形成症的治疗需要有效的,有针对性的疗法.
磁纳米粒子 (MNP) 越来越多地被用于医学应用.
对于血栓溶解的MNP存在有限的审查.

研究的目的:

审查目前MNP在血栓溶解中的应用.
在静态/动态磁场下探索MNP介导的血栓溶解.
讨论将MNP和声场结合在一起的双模式血栓溶解.

主要方法:

对MNP介导血栓溶解的体外和体内研究的综述.
分析使用磁场的MNP导航和控制.
对联合MNP-声场血栓溶解的检查.

主要成果:

对于有针对性的血栓溶解来说,MNP是有前途的.
磁场使MNP导航和陷用于凝块溶解.
双模式血栓溶解可以提高治疗疗效.

结论:

通过MNP介导的血栓溶解是一个具有显著潜力的发展领域.
进一步的研究可以优化MNP向,药物释放和凝块破坏.
本综述为未来基于MNP的治疗方法的临床开发提供了见解.

关键词:

磁性纳米颗粒磁性纳米粒子磁性微气泡是一种微气泡.磁声热溶解是一种磁声热溶解.声纳热溶解 (sonothrombolysis) 是一个非常重要的过程.血栓溶解是一种血栓溶解.血栓溶解剂血栓溶解剂是一种血栓溶解剂.

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