有氧铁氧化细菌分泌的代谢物明显阻碍了非生物铁氧化的代谢物
Isabel R Baker1, Sarick L Matzen2, Christopher J Schuler3
1Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
PNAS nexus
|December 19, 2023
概括
氧化铁的细菌 (FeOB) 分泌的化合物使铁的氧化速度减慢100倍,使得持续的铁 (Fe2+) 可用性. 这种适应有助于这些微生物在富含氧气的环境中壮成长,影响铁的生物可用性.
科学领域:
- 微生物学和地球化学
- 铁的生物地球化学循环.
- 微生物在有氧环境中的适应.
背景情况:
- 铁对生命至关重要,但其生物利用性受到氧化和氧化水中的沉限制.
- 氧化铁氧化细菌 (FeOB) 从铁 (Fe2+) 氧化中利用能量,但面临非生物过程的竞争.
- 一些FeOB在高氧环境中壮成长,这表明了克服快速非生物铁氧化的机制.
研究的目的:
- 调查FeOB是否会改变它们的环境,以限制非生物铁 (Fe2+) 氧化.
- 测试假设FeOB分泌的代谢物 (外甲基) 阻碍了Fe2+的氧化.
- 了解FeOB如何在富含氧气的条件下持续存在,尽管与非生物铁氧化存在竞争.
主要方法:
- 用来自*Ghiorsea bivora*TAG-1 (一种FeOB) 的分泌代谢物化铁铁 (Fe2+) 和氧气.
- 与Fe2+氧化率和沉物特征的比较,含有或不含FeOB外甲基.
- 从TAG-1中生长的铁对的表甲基的分析.
主要成果:
- 在氧气的存在下,*Ghiorsea bivora* TAG-1的氧化铁外甲基增长了Fe2+半衰期的100倍 (从~3到~335天).
- 来自气培养的TAG-1的表甲基对Fe2+氧化没有影响.
- 在氧化铁的外甲基体存在时形成的沉物具有较差的结晶性,与非生物对照中的丰富,矿化铁颗粒不同.
结论:
- 氧化铁的FeOB的外甲基显著阻碍了非生物性铁 (Fe2+) 的氧化,维持了Fe2+的可用性.
- 这种微生物适应使FeOB能够管理氧化还原平衡,并在氧化,富含铁的环境中持续存在.
- 这些发现表明,一种新的机制影响了海洋生态系统中的微生物生命对铁的生物可用性.
更多相关视频
06:52Experimental Column Setup for Studying Anaerobic Biogeochemical Interactions Between Iron OxyHydroxides, Trace Elements, and Bacteria
Published on: December 19, 2017
7.9K
06:17Medium Preparation for the Cultivation of Microorganisms under Strictly Anaerobic/Anoxic Conditions
Published on: August 15, 2019
27.9K
相关概念视频
The Electron Transport Chain
16.8K
The electron transport chain or oxidative phosphorylation is an exothermic process in which free energy released during electron transfer reactions is coupled to ATP synthesis. This process is a significant source of energy in aerobic cells, and therefore inhibitors of the electron transport chain can be detrimental to the cell's metabolic processes.
Inhibitors of the electron transport chain
Rotenone, a widely used pesticide, prevents electron transfer from Fe-S cluster to ubiquinone or Q...
Inhibitors of the electron transport chain
Rotenone, a widely used pesticide, prevents electron transfer from Fe-S cluster to ubiquinone or Q...
16.8K
Bioremediation
18.5K
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
18.5K
Antimicrobial Proteins
1000
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
1000
Necrosis
4.5K
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
4.5K
Electron Transport Chain: Complex III and IV
7.5K
During the electron transport chain, electrons from NADH and FADH2 are first transferred to complexes I and II, respectively. These two complexes then transfer the electrons to ubiquinol, which carries them further to complex III. Complex III passes the electrons across the intermembrane space to Cyt c, which carries them further to complex IV. Complex IV donates electrons to oxygen and reduces it to water. As electrons pass through complexes I, III, and IV, the energy released aids the pumping...
7.5K
Fates of Pyruvate
8.5K
Pyruvate is the end product of glycolysis, where glucose is oxidized to pyruvate, simultaneously reducing NAD+ to NADH. Two molecules of ATP are also produced by substrate-level phosphorylation.
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
8.5K
