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Updated: Jun 15, 2026

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使用动态光散射对菌体生物活性变化的快速评估

Tejas Dharmaraj1,2, Michael J Kratochvil3, Julie D Pourtois4

  • 1Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Beckman Center for Molecular and Genetic Medicine, Stanford, CA 94305, USA.

PNAS nexus
|December 19, 2023
PubMed
概括

动态光散射 (DLS) 评估了菌体的稳定性,并预测了生物活性,这对于开发抗生素耐药细菌的菌体疗法至关重要. 这种方法确保了菌素制剂的质量控制.

关键词:
聚合方式 聚合方式 聚合方式细菌体衰变的细菌体衰变细菌治疗是一种细菌治疗.动态光散射是一种动态光散射.

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Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...