吸烟与慢性鼻炎之间的关联:系统性审查和元分析
Claire Jing-Wen Tan1, Bryan Hao Wei Leow1, Benjamin Kye Jyn Tan1
1Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
The Laryngoscope
|December 19, 2023
概括
吸烟增加了患慢性鼻炎 (CRS) 的几率. 虽然吸烟会影响手术前的生活质量,但它不会影响功能性内镜外科手术 (FESS) 后的结果.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 呼吸系统医学 呼吸系统医学
- 公共卫生 公共卫生
背景情况:
- 慢性鼻炎 (CRS) 是一种常见的上呼吸道炎症疾病.
- 吸烟与CRS患病率和结果之间的关系需要澄清.
研究的目的:
- 为了确定第一手吸烟和CRS的患病率之间的联系.
- 评估吸烟对CRS预后的影响,包括生活质量 (QOL) 和手术结果.
主要方法:
- 系统审查和对PubMed,Embase,SCOPUS和Cochrane图书馆研究的元分析,截至2022年5月.
- 包括23个截面,19个队列,2个病例控制和1个前性临床试验.
- 随机效应的元分析汇集了患病率,吸烟状况与CRS的关联,以及功能性内镜鼻手术 (FESS) 前后的QOL变化.
主要成果:
- 常吸烟者的患病率在CRS患者中为40%,在对照组中为33%.
- 与从未吸烟者相比,活跃吸烟者和过去吸烟者的CRS患病几率明显高 (分别为1.35和1.23).
- 患有CRS的非吸烟者报告了比吸烟者更好的手术前QOL,但FESS后QOL在两组之间是相似的. 吸烟与FESS后的嗅觉或内镜结果没有显著的相关性.
结论:
- 吸烟与更高的患病率和患上CRS的几率增加有关.
- 医疗保健提供者应该认识到吸烟是CRS的诱导因素.
- 吸烟似乎不会对FESS后的鼻科结果产生负面影响.
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