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开发和评估一个MRI无人工物动脉瘤剪辑器

Sebastian Senger¹, Gerrit Fischer¹, Ruben Mühl-Benninghaus²

¹Department of Neurosurgery, Medical School Saarland University, Homburg , Germany.

Operative neurosurgery (Hagerstown, Md.)

|December 19, 2023

概括

与片相比,一种新的碳纤维增强PEEK动脉瘤片显著减少了MRI器件. 这种无金属的剪贴显示了改善动脉瘤手术后后续成像的前景,可能减少侵入性手术.

科学领域:

生物材料工程是生物材料的工程.
医疗器械开发医疗器械开发
放射学放射学是一门学科.

背景情况:

数字减去血管造影 (DSA) 是动脉瘤手术后续的黄金标准,但具有侵入性,涉及辐射暴露.
磁共振血管造影 (MRA) 仅限于传统动脉瘤剪贴的金属工件.
纤维增强塑料的进步为无金属外科手术工具提供了潜力.

研究的目的:

开发和评估一种由碳纤维增强聚乙乙基 (CF-PEEK) 制成的新型无金属动脉瘤片原型.
在MRI中评估CF-PEEK剪辑器与标准剪辑器相比的工件减少和生物相容性.
确定使用CF-PEEK剪贴用于改善术后动脉瘤后续治疗的可行性.

主要方法:

一个CF-PEEK动脉瘤剪贴原型被设计和制造.
实验室幻影研究使用MRI和微断层扫描进行,以评估文物.
在老鼠体内研究评估了生物相容性和MRA疗效,将CF-PEEK剪贴与剪贴和线进行了比较.

主要成果:

幻影研究表明,CF-PEEK剪辑器没有任何工件.
CF-PEEK剪贴显示可靠的紧和重新打开,尽管力量减少了.
在体内MRA证实了CF-PEEK组的动脉封闭成功,并统计显著地减少了剪切器件 (P < .01). 生物相容性与相匹配.

结论:

开发的CF-PEEK无人工物动脉瘤剪贴是实用的和可行的.
需要进一步开发以解决减少的紧力.
这种无金属的剪贴有可能提高MRI质量,减少对DSA的依赖,用于动脉瘤的随访.

关键词:

动脉瘤剪片的剪片没有人工制品的文物.生物相容性生物相容性 PEEK 纤维增强塑料的塑料.脉冲技术是一种脉冲技术.

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Magnetic Resonance Imaging

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