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克罗恩病术后复发的结果和终点:系统性审查和共识会议
Nassim Hammoudi1, David Sachar2, Geert D'Haens3
1Department of Gastroenterology, Hôpital Saint-Louis, Université Paris Cité, Paris, France.
Journal of Crohn's & colitis
|December 19, 2023
概括
对于克罗恩氏病 (CD) 结肠直肠切除术的术后结果进行标准化至关重要. 建议使用内镜和成像来确定复发,在试验中超越不可靠的临床症状.
科学领域:
- 胃肠病学 胃肠病学
- 炎症性肠病研究研究
- 外科手术的结果
背景情况:
- 在克罗恩病 (CD) 中,大结节切除后的结果是高度可变的.
- 缺乏对CD术后复发的标准化定义.
- 国际炎症肠道疾病研究组织 (IOIBD) 终点工作组召开会议,以解决这一差距.
结论:
- 监管机构往往倾向于临床评估,而不是仅仅依赖内镜检查的主要终点.
- 有共识,必须根据内镜和/或成像定义术后终点.
- 这项工作旨在为CD术后管理建立标准化,基于证据的终点.
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