性别差异在ICU输出管失败风险中的性别差异
Arnaud W Thille1,2, Florence Boissier3,4, Rémi Coudroy3,4
1Service de Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Poitiers, 2 Rue La Milétrie, 86021, Poitiers Cedex, France. aw.thille@gmail.com.
Annals of intensive care
|December 19, 2023
概括
在重症监护室 (ICU) 进行机械通风后,男性性别独立地与更高的再输管风险有关. 进一步的研究应该检查性别在重症患者的结果中的作用.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 临床预后 临床预后
背景情况:
- 关于在重症监护室 (ICU) 接受机械呼吸的患者预后的性别差异的研究有限.
- 在ICU内,出失败风险的潜在性别差异需要进行调查.
研究的目的:
- 评估输出管失败的风险,定义为在7天内重新输入管,按性别分层.
- 调查高风险机械通风患者的潜在性别差异.
主要方法:
- 一项涉及高风险ICU患者的大型临床试验的特例后分析.
- 主要结局:在输出管后7天内重新输入管.
- 多变量逻辑回归用于识别重新灌输的独立预测因素.
主要成果:
- 与女性相比,男性 (66%) 在48小时后的再灌输率显著更高 (11.0%对6.0%).
- 7天后的再输管率在性别之间没有显著差异 (16.7%对11.1%).
- 男性的性别独立地与7天再灌输风险增加1.70倍相关 (aOR1.70;P=0.048).
结论:
- 性别在高风险的ICU患者小组中独立地与再输管风险相关.
- 这些发现表明,在输出管失败中,存在潜在的性别差距.
- 未来的研究应该系统地评估性对重症患者结局的影响.
相关概念视频
Endotracheal Tube Extubation
719
Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
719
Endotracheal Intubation II: Nursing Management
696
Endotracheal intubation is a critical procedure that can be lifesaving for many patients with respiratory distress or failure. The role of nursing in managing endotracheal tubes is pivotal, as it involves pre-intubation preparation, assisting during the procedure, and post-extubation care.
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
696
Endotracheal Intubation I: Procedure
1.4K
Endotracheal or ET intubation is a critical medical procedure used to secure a patient's airway, often in acute respiratory distress, apnea, upper airway obstruction, ineffective clearance of secretions, high risk for aspiration, or during general anesthesia.
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
1.4K
Mechanical Ventilation II: Invasive Ventilation
151
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
151
Acute Respiratory Failure-II
239
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
239
Acute Respiratory Failure-I
213
Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
213


