维生素D缺乏是否会影响关节骨折患者的功能结果? 对队列研究的元分析
R Llombart1, G Mariscal2, C Barrios3
1Orthopedic Surgery Department, University Clinic of Navarra, Pamplona, Spain.
Journal of endocrinological investigation
|December 19, 2023
概括
部骨折患者的维生素D缺乏与功能能力和生活质量恶化有关. 查和优化维生素D水平可能会改善康复和独立.
科学领域:
- 整形外科 整形外科 整形外科
- 内分泌学 在内分泌学.
- 老年病的医生 老年病的医生
背景情况:
- 在部骨折患者中,维生素D缺乏是普遍存在的.
- 它可能会影响功能恢复和生活质量 (QOL).
研究的目的:
- 通过元分析量化维生素D缺乏对骨折后身体功能和质量生活的影响.
主要方法:
- 在PubMed,EMBASE,Scopus和Cochrane图书馆进行了搜索.
- 包括的研究将维生素D缺乏与部骨折患者的正常水平进行了比较,具有功能性结果.
- 使用审查经理进行了元分析,评估异质性和出版偏见.
主要成果:
- 分析了7项涉及1972名患者的研究.
- 在行走能力或住院期间没有发现显著差异.
- 维生素D缺乏与功能能力和QOL显著下降相关.
结论:
- 维生素D缺乏会对功能能力和关节骨折后的QOL产生负面影响.
- 查和优化维生素D水平可以帮助康复和独立.
- 补充剂可以减少关节骨折患者的长期负担.
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