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微波诱导的热声内镜用于在深层组织中检测结肠直肠瘤

Huimin Zhang, Mingyang Ren, Yu Wang

IEEE transactions on medical imaging

|December 19, 2023

概括

一种新的微波诱导热声学 (TA) 内镜 (MTAE) 提供比光学内镜更深入的结直肠瘤成像. 这个TA内镜通过检测电磁组织参数的变化来可视化瘤的进展.

科学领域:

生物医学工程生物医学工程
医疗成像医学成像
胃肠病学胃肠病学

背景情况:

由于光散射,光学内镜仅限于表面组织成像.
现有的方法对于深部结直肠瘤缺乏足够的深度和对比度.

研究的目的:

开发和评估微波诱导热声学内镜 (MTAE),用于增强结直肠成像.
为了克服当前内镜方式的深度和对比度限制.

主要方法:

集成了一个用于微波辐射的单极套天线和用于信号检测的侧向超声波传感器.
开发了一种MTAE系统,将微波激发和声学检测相结合用于成像.
在体内使用结直肠瘤的子评估了系统.

主要成果:

MTAE系统在软组织中产生了几厘米深的具有介电对比度和高空间分辨率的图像.
通过检测电磁组织参数的变化,在体内成功可视化结直肠瘤的进展.
与光学内镜相比,展示了更高的成像深度,与超声波内镜相比,改善了对比度.

结论:

该MTAE系统克服了当前内镜成像深度限制.
MTAE有潜力检测深层结直肠瘤和它们对邻近结构的入侵.
该技术显示出在结直肠癌诊断中临床应用的巨大潜力.

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