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Updated: Jul 8, 2025

Combined DNA-RNA Fluorescent In situ Hybridization FISH to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
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在小鼠X染色体无活化过程中Rlim-Rex1轴的作用.

Feng Wang1, Ashmita Chander2, Yeonsoo Yoon3

  • 1Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605.

Proceedings of the National Academy of Sciences of the United States of America
|December 19, 2023
PubMed
概括

在早期的雌性小鼠胚胎中,Rlim-Rex1轴调节印记X染色体失活 (iXCI). 然而,独立于Rlim的Rex1下调,特别是在表皮质细胞中,阻止其参与随机XCI (rXCI).

关键词:
雷克斯1 / Zfp42 的时间.在Rlim/Rnf12中使用.一个X染色体不活化.胚胎外的生体外皮.植入植入植入植入植入植入植入植入植入

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