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增强的TLR7信号质 BCR激活的B细胞在慢性移植对宿主疾病的效应器功能

Sonali J Bracken1, Amy N Suthers2, Rachel A DiCioccio2

  • 1Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center, Durham, NC.

Blood advances
|December 19, 2023
PubMed
概括

慢性移植对宿主疾病 (cGVHD) 涉及具有增强的托尔类受体7 (TLR7) 信号的B细胞,有助于自身免疫反应. 在B细胞中异常的TLR7激活促进了cGVHD中的效应器功能.

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