基本的富辛染料作为第一个光体,用于在水果皮和尿液样本中光学检测吗啡
Amr A Essawy1, I H Alsohaimi1, Hassan M A Hassan1
1Chemistry Department, College of Science, Jouf University, PO. Box 72341Sakaka,Aljouf,Kingdom of Saudi Arabia.
Analytical chemistry
|December 19, 2023
概括
基本 (BF) 是一种新的光学传感器,用于通过光检测形态素 (MOR). 这种敏感和选择性的方法可以在各种样本中准确量化morpholine,满足监管标准.
科学领域:
- 分析化学 分析化学
- 频谱学是一种光谱学.
- 化学传感器 化学传感器
背景情况:
- 吗啡 (MOR) 是一种广泛使用的工业化学物质,具有潜在的健康影响.
- 对于环境和食品安全而言,准确和灵敏的吗啡检测方法至关重要.
- 现有的检测方法可能缺乏灵敏度,选择性或实际应用的实用性.
研究的目的:
- 开发和验证一种用于检测形态素的新型光谱计量方法.
- 为了利用基本 (BF) 作为光光学传感器用于morpholine.
- 评估开发方法的敏感性,选择性和适用性.
主要方法:
- 使用基本素 (BF) 作为光探针进行光谱测量分析.
- 优化实验参数,包括溶剂,BF度和加法顺序.
- 使用果皮提取物和人类尿液的样方法的验证.
主要成果:
- 在morpholine的存在下,BF证明了选择性的光火.
- 该方法显示了两种度范围的线性: 5 × 10−9 到 1.0 × 10−7 mol L−1 和 2.0 × 10−7 到 3 × 10−6 mol L−1.
- 已达到2.0 × 10−9 mol L−1的检测极限 (LOD) 和6.66 × 10−9 mol L−1.1的量化极限 (LOQ).
- 在现实世界样本矩阵中证明了高准确度和精度.
结论:
- 基本的富辛作为一个有效和敏感的光传感器用于检测morpholine.
- 开发的光谱测方法快速,有选择性,适合实际应用.
- 该方法符合美国食品和药物管理局 (FDA) 在各种矩阵中对形态素分析的要求.
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