与COVID-19相关的肺胸部的临床特征:两个中心的回顾性分析
Kohei Fujita1, Toshiyuki Iwata2, Osamu Kanai1
1Division of Respiratory Medicine, Center for Respiratory Diseases, National Hospital Organization Kyoto Medical Center, Kyoto, Japan; Department of Infectious Diseases, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
肺胸炎是一种严重的COVID-19并发症,经常影响需要氧气的中度至重度疾病患者. 这种情况往往发生在诊断后一个月内,并携带高死亡率,需要临床警.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 肺胸炎是2019年冠状病毒疾病 (COVID-19) 的一种已知的并发症.
- 与COVID-19相关的肺胸炎的具体临床特征仍然不完全理解.
- 本研究旨在阐明这些特征.
研究的目的:
- 在被诊断为COVID-19的患者中调查肺胸部的临床特征.
- 为了确定与COVID-19相关的肺胸相关的风险因素,治疗方法和结果.
主要方法:
- 在两所机构对21名在COVID-19诊断后六个月内患上肺胸病的患者进行了回顾性分析.
- 收集的数据包括背景因素,COVID-19的严重程度,治疗,肺胸部发病时间和预后.
主要成果:
- 肺胸部发病率为0.89%,患者平均年龄为72.5岁;90.5%是男性,76.1%有吸烟史.
- 大多数患者 (76%) 患有中度至重度的COVID-19,需要氧化,并接受抗病毒药物,免疫抑制剂和/或德克萨米他治疗.
- 肺胸部发作发生在COVID-19诊断后的15天 (86%在一个月内),30天死亡率为28.6%.
结论:
- 与COVID-19相关的肺胸炎在需要氧气的中度至重度疾病患者中更为普遍.
- 肺胸炎的发病通常发生在COVID-19诊断后一个月内.
- 这种并发症是严重的,与显著的死亡率相关,需要提高临床意识.
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