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环境暴露于和作为可能导致眼睛疾病的潜在原因

Moein Ebrahimi¹, Maryam Ebrahimi², Joëlle E Vergroesen³

¹School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Network of Immunity in Infection, Malignancy, and Autoimmunity, Universal Scientific Education and Research Network (USERN), Tehran, Iran.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

|December 19, 2023

概括

每天接触工业来源的和可能会损害视力. 这篇评论探讨了这些重金属如何导致与年龄相关的眼睛疾病,如黄斑变性,白内障和绿内障.

科学领域:

环境毒理学环境毒理学
眼科医生眼科眼科
细胞生物学细胞生物学

背景情况:

世界各地的人口每天都面临着和的暴露,主要是由于工业活动和气候变化.
临床前和临床研究越来越多的证据表明,重金属,特别是和在各种眼睛疾病的发展中起着重要作用.
对这些重金属的高暴露越来越多地与视力受损的风险增加有关.

研究的目的:

调查和在与年龄有关的眼病病因和进展中的潜在参与.
阐明和对眼睛细胞的影响机制.
提供这些金属可能导致眼睛损伤的病理途径的全面概述.

主要方法:

临床前和临床研究的文献综述.
对重金属暴露和眼睛健康现有研究的分析.
对和对眼睛细胞和组织的影响的综合数据.

主要成果:

和暴露与与年龄相关的黄斑变性,白内障和玻璃眼相关的风险增加有关.
这些重金属可以诱导细胞损伤和各种眼睛组织的功能障碍.
特定的病理机制,包括氧化应激和炎症,都与重金属诱导的眼睛损伤有关.

结论:

和是与年龄相关的眼睛疾病的重要环境风险因素.
了解这些金属对眼细胞的毒理作用对于制定预防策略至关重要.
需要进一步的研究,以充分阐明重金属暴露和眼睛疾病病原体之间的复杂相互作用.

关键词:

与年龄相关的黄斑变性.白内障是什么?白内障是什么?白内障是什么?环境污染环境污染眼光障碍症眼光障碍症眼光障碍症安全的环境安全的环境

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