[基于多重数据挖掘的国家专利数据库中治疗心痛的中国草药化合物处方的药物规则]
Cheng-Sheng Chen1, Kang Jing1, Yan-Meng Guo1
1Hubei University of Chinese Medicine Wuhan 430000, China.
这项研究分析了中国的草药专利,以揭示心痛的药物规则,识别了像Salviae Miltiorrhizae Radix et Rhizoma这样的关键草药和常见的综合征,如血液静止. 这些发现为临床治疗和新药开发提供了洞察力.
科学领域:
- 传统中国医药 传统中国医药
- 药理学 药理学是指药理学的学科.
- 数据挖掘 数据挖掘
背景情况:
- 胸痛治疗往往涉及中国草药化合物处方.
- 了解药物规则对于有效治疗和药物开发至关重要.
研究的目的:
- 通过使用专利数据,探索中国草药化合物处方治疗心痛的药物规则.
- 确定用于心痛治疗的核心药物组合和关联规则.
主要方法:
- 来自中国国家知识产权管理局数据库的中国草药化合物专利对心痛的数据挖掘.
- 分析包括主要综合征,药物使用频率,集群分析和关联规则分析.
主要成果:
- 分析了涉及815种药物的636项专利.
- 阻碍心脏的血液静止和 Qi 缺乏和血液静止是主要的综合征.
- 萨尔维亚 (Salviae Miltiorrhizae Radix et Rhizoma) 草根,楚安雄草根和诺托金森草根是关键的草药,通常与调色剂结合.
结论:
- 胸痛的药物规则与临床实践保持一致,强调激活血液,缓解静止和 tonifying 草药.
- 确定了新的化合物处方和药物组合,为临床应用和新药开发提供了洞察力.
更多相关视频
07:20Author Spotlight: Integrating Traditional Chinese Medicine with Modern Pharmacology and Genomics for Assessing Postmenopausal Osteoporosis in Mice
Published on: August 23, 2024
08:15Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease
Published on: May 10, 2024
相关概念视频
Antianginal Drugs: Nitrates and β-Blockers
Organic nitrates, such as nitroglycerin, play a pivotal role. Once metabolized, they liberate nitric oxide, a molecular marvel. Nitric oxide triggers guanylyl cyclase and augments cGMP production. This biochemical cascade orchestrates the relaxation of vascular smooth muscles, ushering in vasodilation and enhancing coronary blood flow....
Antihypertensive Drugs: Direct Renin Inhibitors
Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors
Antianginal Drugs: Calcium Channel Blockers and Ranolazine
CCBs, a diverse class that includes dihydropyridines (nifedipine) and diphenylalkylamines (verapamil and diltiazem), exert their effect by blocking calcium channels in cardiac and smooth muscle cells. This...
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
