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极化转移方法用于流动混合物的定量分析,使用CNMR光谱仪¹³

Johnnie Phuong^1,2, Zeno Romero^1,2, Hans Hasse^1,2

¹Laboratory of Engineering Thermodynamics (LTD), RPTU Kaiserslautern, Kaiserslautern, Germany.

Magnetic resonance in chemistry : MRC

|December 19, 2023

概括

基板NMR光谱在光谱分辨率和信号强度方面的挑战是通过使用1H-13C偏振转移方法克服的. 这种技术在工艺监测中增强了静态和流动样本的定量分析.

科学领域:

分析化学分析化学
频谱学是一种光谱学.

背景情况:

基板NMR光谱技术提供了过程监测的优势,但面临着局限性.
在1H NMR中低光谱分辨率和13C NMR中低信号强度阻碍了定量分析.
在13C NMR流动样本的预磁化方面存在挑战.

研究的目的:

为了证明1H-13C偏振转移方法在克服基板NMR限制方面的有效性.
为了评估使用PENDANT增强的13C NMR的三元混合物的定量分析.
评估这些方法对流动样本的实时过程监测的适用性.

主要方法:

使用1特斯拉 (T) 基板NMR光谱仪与PENDANT (在附加的核测试中培养的极化增强) 序列.
在静止和流量条件下分析了三元试验混合物.
与PENDANT增强的13C NMR结果与标准的1H和13C NMR结果进行了比较,并进行了重力测量分析.

主要成果:

用PENDANT增强的13C核磁共振成功解决了低光谱分辨率和信号强度问题.
混合物的定量分析在静止和流体实验中都是准确的.
连续稀释实验证明了在流量设置中有效实时监测混合物成分.

结论:

1H-13C极化转移方法,特别是PENDANT,显著提高了基板NMR能力.
这些方法为定量分析提供了可靠的解决方案,特别是流动样本.
该研究强调了极化转移在使用基准NMR仪器进行定量过程分析方面的巨大潜力.

关键词:

1H; 13C 的时间.基板NMR可以使用.流量NMR流量NMR流量极化转移转移的极化是什么过程监控过程监控过程监控定量分析量化分析

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