相关实验视频
Updated: Jul 8, 2025

05:39
A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
Published on: November 30, 2021
3.6K
极低出生体重婴儿的胃肠道穿孔:中国的一项单中心回顾性研究
Wei Feng1, Hong Zhang2, Huan Yan1
1The Department of Pediatric Surgery, Chengdu Women's and Children' Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 611731, China.
Pediatrics and neonatology
|December 19, 2023
概括
胃肠道穿孔是极低出生体重的婴儿的关键威胁. 败血症和血液动力学显著的动脉管是关键的危险因素,而像布洛芬和输血等治疗可以提高生存率.
科学领域:
- 新生儿科学 新生儿科学
- 儿科手术 儿科手术
- 临界护理医学 临界护理医学
背景情况:
- 极低出生体重婴儿 (ELBWI) 的胃肠道穿孔 (GIP) 是一种危及生命的疾病,死亡率高.
- 具有迅速发病和严重并发症的特征,GIP需要了解其风险因素和管理策略.
研究的目的:
- 为了研究ELBWI中肺皮的临床特征.
- 为了确定在出生时体重非常低的早产婴儿中GIP的危险因素.
- 分享在ELBWI管理GIP的外科经验.
主要方法:
- 从2014-2021年对ELBWI与GIP (出生体重<1000g) 的回顾性研究.
- 使用多重逻辑回归分析识别风险因素.
- 使用Kaplan-Meier和Cox多变量回归模型进行生存分析.
主要成果:
- 在ELBWI中,GIP的重大风险因素包括血液动力学上显著的专利性动脉管 (hsPDA) 和败血症.
- 腹腔内出血,败血症和GIP对ELBW婴儿存活率产生负面影响.
- 布洛芬和输血表明对生存有有益影响.
结论:
- GIP显著威胁到 ELBW 婴儿存活率,hsPDA 和败血症作为易感因素.
- GIP的独特临床特征需要量身定制的外科干预.
- 了解风险因素和生存预测因素对于ELBWI的GIP管理至关重要.
相关概念视频
Esophageal Perforation-I: Introduction
98
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
98
Esophageal Perforation-II: Clinical Manifestations and Management
65
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
65

