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通过其 PDZ 域对 LIM 激酶进行自我调节

Gabriela Casanova-Sepúlveda1, Joel A Sexton2, Benjamin E Turk2

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA.

Nature communications
|December 19, 2023
PubMed
概括

LIMK2的PDZ域具有独特的结构,这表明它具有新的监管作用. 这个域对LIMK1和LIMK2自身调节至关重要,影响着actin细胞骨动力学.

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