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Updated: Jul 8, 2025

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核RPSA感知病毒核酸,以促进先天的炎症反应

Yan Jiang1, Siqi Sun1, Yuan Quan1

  • 1Department of Immunology, Center for Immunotherapy, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.

Nature communications
|December 19, 2023
PubMed
概括

研究人员发现40S核糖体蛋白SA (RPSA) 作为核传感器,在病毒感染期间触发促炎细胞因子. 骨髓细胞中的RPSA缺乏减少了对HSV-1和IAV等核复制病毒的炎症反应.

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