智力和发育障碍患者的COVID-19后疾病风险:一项涉及36308名患者的回顾性队列研究
Ting-Hui Liu1, Po-Yu Huang2, Jheng-Yan Wu3
1Department of Psychiatry, Chi Mei Medical Center, No 901, Chunghwa Road, Yongkang District, Tainan City 710, Taiwan.
BMC medicine
|December 20, 2023
概括
智力和发育障碍 (IDD) 个体面临患COVID-19后疾病的风险更高. 这项研究强调,在SARS-CoV-2感染后的IDD人口中,疲劳和认知问题等症状的患病率增加.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 关于残疾人的研究.
背景情况:
- 没有先前的研究检查了智力和发育障碍 (IDD) 患者的COVID-19后情况.
- 了解IDD患者的这些情况对于改善护理规划和承认这一弱势群体至关重要.
- 这项研究解决了一个关键的差距,通过调查IDD患者中COVID-19后疾病的患病率和风险.
研究的目的:
- 调查智力和发育障碍 (IDD) 患者中COVID-19后疾病的患病率.
- 为了比较患有IDD的患者与普通人群中患有COVID-19后疾病的风险.
主要方法:
- 利用TriNetX网络识别了患有和没有IDD的COVID-19患者.
- 在IDD和非IDD组之间比较了发展任何COVID-19后疾病的风险.
- 随访期为SARS-CoV-2感染后的90-180天.
主要成果:
- 患有IDD的患者显示,COVID-19后疾病的患病率显著更高 (HR:1.120).
- 在IDD患者中观察到异常呼吸,腹部症状,疲劳,焦虑/抑郁,认知症状,肌痛,睡眠障碍和咳的风险增加.
- 具体增加的风险包括认知症状 (HR: 1.828) 和睡眠障碍 (HR: 1.481).
结论:
- 智力和发育障碍患者在感染SARS-CoV-2后可能面临COVID-19后疾病的风险增加.
- 这些发现强调了针对IDD患者经历长期COVID的有针对性的监测和支持的必要性.
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