在绝经前妇女中,HT,BMI和过敏性鼻炎之间的关联
Jingyi Liu1, Tingting Ma1, Xiaoxue Wang2
1Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038, China.
概括
激素治疗 (HT) 可能会增加过敏性鼻炎 (AR) 风险,特别是在瘦身的绝经前期妇女中. 肥胖可能会减轻这种风险,这表明HT和BMI在AR发展中的相互作用.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 过敏学 过敏学
- 肥胖医学 肥胖医学
背景情况:
- 激素治疗 (HT) 和肥胖越来越多地与过敏性鼻炎 (AR) 相关.
- 了解HT,体重指数 (BMI) 和绝经前妇女的AR之间的相互作用至关重要.
研究的目的:
- 在绝经前妇女中调查HT,BMI和AR之间的关联和相互作用.
- 为了确定BMI是否会改变HT对AR风险的影响.
主要方法:
- 在访问过敏和妇科病房的950名患者中进行了横截面调查.
- 用后勤回归分析数据,用BMI tertiles进行分层分析.
- 该研究评估了HT,BMI和AR患病率和症状之间的关系.
主要成果:
- 高血压与AR (OR=1.51),喘 (OR=3.61) 和伴随症状 (OR=3.54) 的风险增加有关.
- 在瘦女性中,HT显著增加了AR的风险 (OR=2.26),其过程 (OR=2.54),花粉热 (OR=2.54) 和症状 (OR=2.26).
- 观察到HT和BMI之间的相互作用,特别是影响RA过程,花粉热,以及瘦女性的伴随症状.
结论:
- 在绝经前妇女中,使用HT与AR的风险更高有关,特别是在瘦人群中.
- 在HT和BMI之间存在显著的相互作用,影响AR风险和呈现.
- 需要进一步的研究来探索HT和肥胖可能影响AR的常见途径.
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