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相关概念视频

Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

9.3K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
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Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

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Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
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Olfaction01:25

Olfaction

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The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
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Nonconscious Mimicry01:13

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Nonconscious mimicry occurs when individuals alter their mannerisms to match the behaviors and expressions of those nearby, without intention.
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Prosopagnosia01:24

Prosopagnosia

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Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
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Association Areas of the Cortex01:21

Association Areas of the Cortex

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Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
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相关实验视频

Updated: Jul 8, 2025

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time
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在parosmia中的功能连接模式.

Divesh Thaploo1, Akshita Joshi2, Eren Yilmaz3

  • 1Smell & Taste Clinic, Department of Otorhinolaryngology, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany. Taploodivesh4@gmail.com.

Behavioral and brain functions : BBF
|December 20, 2023
PubMed
概括
此摘要是机器生成的。

嗅觉障碍帕洛斯米亚 (parosmia) 与嗅觉区域的大脑连接性降低有关. 这项研究使用功能性MRI显示记忆,决策和嗅觉处理中心之间的信息流动受损在患有parosmia的患者.

关键词:
执行控制 执行控制功能性的连接性 功能性的连接性缺血症是什么意思 缺血症是什么意思帕洛斯米亚 (Parosmia) 是一种严重的疾病.突出 突出 突出 突出

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相关实验视频

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科学领域:

  • 神经科学是一个神经科学.
  • 嗅觉研究 嗅觉研究
  • 医疗成像医学成像

背景情况:

  • 帕洛斯米亚是一种质的嗅觉功能障碍,其特点是对气味的感知有所扭曲.
  • 了解帕洛斯米亚中中枢神经系统的变化对于诊断和治疗至关重要.

研究的目的:

  • 通过静止状态的功能连接来研究中枢神经系统内嗅觉处理的变化.
  • 为了确定受帕洛斯米亚影响的特定大脑网络和区域.

主要方法:

  • 一项涉及145名被诊断患有帕洛斯米亚的患者的横截面研究.
  • 标准化问卷和嗅觉测试 (嗅探棒) 用于诊断.
  • 休息状态功能磁共振成像 (fMRI) 扫描使用3T扫描仪获得.

主要成果:

  • 全脑分析显示,突出和执行控制网络的功能连接性减少.
  • 对感兴趣区域的分析显示,初级/二级嗅觉区域 (极,上边环,轨道前皮层) 和嗅觉皮层 (皮层) 之间的连接性下降.

结论:

  • 患有帕洛斯米亚的患者表现出记忆,决策中心和初级/二级嗅觉区域之间的功能连接性降低.
  • 这些发现表明,在parosmia中,嗅觉感知和整合的基础是神经通路的破坏.