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Updated: Aug 7, 2026

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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在患有高级固体瘤的患者中,以模型为基础选择皮下尼沃卢马布剂量

Yue Zhao1, Kinjal Sanghavi1, Amit Roy1

  • 1Bristol Myers Squibb, Princeton, New Jersey, USA.

Clinical pharmacology and therapeutics
|December 20, 2023
PubMed
概括

皮下用尼沃卢马布 (nivolumab),与氨基酶 (hyaluronidase) 配合或不配合使用,显示出可预测的药理动力学 (PK). 这种皮下配方,每四周服用1200毫克,为癌症治疗提供了静脉注射尼沃卢马布的可行替代方案.

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