在急性缺血性中风患者中,身体组成和白质强度之间的相关性
Bin Wu1,2, Dong Huang1,2,3, Ziwei Yi4
1Department of Neurology, Hunan University of Medicine General Hospital, Huaihua, People's Republic of China.
Medicine
|December 20, 2023
概括
在急性缺血性中风患者中,较低的骨密度与更严重的白质超强度 (WMH) 有关. 这一发现凸显了骨密度作为中风患者中WMH负担的关键因素.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 老年学是一门学科.
背景情况:
- 白质高强度 (WMH) 负担是缺血性中风的危险因素.
- WMH和肥胖之间的关联是复杂的,可能会受到身体成分的影响.
- 对急性缺血性中风 (AIS) 患者的WMH负担和特定身体成分的系统评估是有限的.
研究的目的:
- 调查急性缺血性中风 (AIS) 患者的白质强度过高 (WMH) 负担和分解的身体成分之间的关系.
- 为了确定特定的身体组成元素是否独立地与AIS患者的WMH严重程度有关.
主要方法:
- 分析了352名AIS患者的队列.
- 身体组成 (皮下脂肪组织,直立脊柱肌肉区域,骨密度) 通过计算机断层扫描进行评估.
- 使用Fazekas尺度对液体减弱反转恢复MRI进行WMH负担的评估,分类严重程度.
主要成果:
- 与没有轻度WMH的患者相比,中度至重度WMH的患者表现出较低的骨密度,更小的勃起脊柱肌面积和减少的皮下脂肪组织.
- 后勤回归显示,骨密度与中度至严重的整体WMH独立相关 (OR=0.98,95% CI:0.972-0.992,P<.001).
- 在骨密度和周周结膜性WMH (P-WMH) 严重程度之间观察到类似的独立关联.
结论:
- 骨密度是急性缺血性中风患者白质过强度严重性的独立预测因素.
- 减少骨密度与增加WMH负担有关,这表明骨完整性和脑血管健康之间存在潜在联系.
- 进一步的研究是有必要的,以探索骨密度和WMH在AIS的背景下连接的潜在机制.
相关概念视频
Characteristics and Functions of Blood
Blood is specialized connective tissue comprising about 8% of the body mass. It has a thick, liquid extracellular matrix that contains cells, dissolved proteins, and electrolytes, making it five times more viscous than water. Blood is warm, around 38°C, and has an alkaline pH ranging from 7.35 to 7.45.
The primary function of blood is to transport oxygen and carbon dioxide between tissues and the lungs. Oxygenated blood is bright red, while oxygen-depleted blood is darker. It also carries...
The primary function of blood is to transport oxygen and carbon dioxide between tissues and the lungs. Oxygenated blood is bright red, while oxygen-depleted blood is darker. It also carries...
Structure and Function of Leukocytes
An adult in good health typically has between 4,500 and 11,000 leukocytes, or white blood cells, per microliter of blood, which constitutes about 1% of the total blood volume. Unlike red blood cells, white blood cells contain a nucleus and other cellular organelles but do not have hemoglobin. Most white blood cells reside in connective tissues, particularly in lymphatic organs such as the lymph nodes, with only a small fraction present in circulating blood.
White blood cells protect the body...
White blood cells protect the body...
Disorders of Hemostasis
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Blood Transfusion
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Myocarditis I: Introduction
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...


