儿童急性胰腺炎 - - 一项国际比较研究和两个城市的故事
Adeline Salim1, Ampaipan Boonthai2, Pornthep Tanpowpong3
1Department of Paediatric Surgery, Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, UK.
儿童急性胰腺炎的原因在英国和泰国之间有所不同,泰国的死亡率与慢性疾病有关. 早期诊断和局部因素影响结果.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 儿童急性胰腺炎 (AP) 带来了独特的病因和管理挑战.
- 进行比较研究对于了解儿科AP的地理差异至关重要.
研究的目的:
- 为了比较导致儿科急性胰腺炎病因,管理和临床结果的因素.
- 确定英国和泰国的主要中心之间的AP介绍和结果的差异.
主要方法:
- 在2006-2016年间被诊断患有AP的儿科患者 (<18岁) 的回顾性分析.
- 数据收集包括病因因素,诊断方法,疾病严重程度,并发症和死亡率.
- 来自利物浦 (英国) 和曼谷 (泰国) 的患者之间的统计比较.
主要成果:
- 病因学有显著的差异:泰国的药物和胆固醇囊与英国的胆结石病和药物 (P<0.01).
- 在英国,超声波的使用率更高 (74.3%与49.1%,P<0.01).
- 虽然大多数病例是轻微的,但泰国的死亡率明显高 (27.8%与9.5%,P=0.02),与并发症有关.
结论:
- 儿科急性胰腺炎的病因在英国和泰国之间有所不同.
- 当地的患者因素和医疗保健途径可能会影响诊断和管理.
- 在泰国,较高的死亡率与脆弱儿科人口的潜在慢性疾病有关.
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