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验证单个参考可变翻转角度 (SR-VFA) 动态T1映射与T2 *使用新型旋转幻影的校正.

Michael A Malmberg1,2, Henrik Odéen2, Lorne W Hofstetter3

  • 1Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.

Magnetic resonance in medicine
|December 20, 2023
PubMed
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单个参考可变翻转角度 (SR-VFA) T1映射,与T2 *校正,准确地测量T1值在逆转恢复 (IR) 参考测量的10%以内. 这种方法在MRI应用中显示出动态T1映射的前景.

科学领域:

  • 磁共振成像 (MRI) 是一种磁共振成像技术.
  • 量化MRI是指数量化的MRI.
  • 生物医学工程 生物医学工程

背景情况:

  • 精确的T1映射对于各种MRI应用至关重要,包括组织表征和对比剂量化.
  • 传统的T1映射技术可能耗时或易受文物损害.
  • 动态T1映射提供了在成像中改善时间分辨率的潜力.

研究的目的:

  • 为了验证单个参考变量翻转角度 (SR-VFA) 动态T1映射与反转恢复 (IR) T1测量.
  • 评估T2 *校正对SR-VFA T1映射的准确性的影响.
  • 评估SR-VFA T1映射在不同旋转速度和回声时间 (TE) 下的性能.

主要方法:

  • 使用了一种定制的agar幻影,其空间梯度为T1放松率.
  • 获得了反转恢复 (IR) T1,可变翻转角度 (VFA) T1和B1+的测量结果.
  • 在幻影旋转过程中获得了多回声堆的辐射动态图像,并计算了B1+-校正的SR-VFA和SR-VFA-T2 * T1地图并与IR T1地图进行了比较.
关键词:
具有MRI兼容性的电机.准确性和精度的准确性和精度.艾加尔 幻影 幻影动态T1映射的动态T1映射定量T1映射的量化T1映射单个参考变量的翻转角度.

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主要成果:

  • 无论是VFA和SR-VFA-T2 * T1地图,都在低旋转速度下实现了IR T1测量的10%以内的精度 (平均精度:分别为2.3%±2.6%和2.8%±2.6%).
  • 由于时间光滑,旋转速度的增加降低了准确性,特别是在T1斜率不恒定的情况下.
  • *校正始终提高了SR-VFA T图的准确性和精度,特别是在较晚的回声时间.

结论:

  • * 动态T映射显示了在亚格幻影中的10%的参考IRT测量的准确性.
  • 这种方法对旋转速度和回声时间敏感,T2 * 校正提高了性能.
  • 需要在混合脂肪-水幻象和体内进行进一步的验证.