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在全甲状腺切除术后进行甲状腺激素替代治疗的临床审计
Islam Mansy1, Abdelfatah M Elsenosy2, Eslam M Hassan3
1General Surgery and Surgical Oncology, Maadi Armed Forces Medical Complex, Cairo, EGY.
Cureus
|December 20, 2023
概括
在甲状腺癌手术后根据患者体重优化甲状腺激素替代剂量 (THR) 将甲状腺刺激激素 (TSH) 水平正常化. 基于体重的THR对于在甲状腺切除术后治疗甲状腺功能低下症至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 临床审计 临床审计
背景情况:
- 甲状腺激素替代疗法 (THR) 是甲状腺切除术后患有甲状腺炎的患者的标准疗法.
- 剂量调整对于治疗甲状腺癌幸存者的甲状腺功能低下症至关重要.
研究的目的:
- 为了审计基于体重的THR对甲状腺刺激激素 (TSH) 水平的影响.
- 确保THR符合国家健康和护理卓越研究所和美国甲状腺协会的指导方针.
主要方法:
- 门诊记录的回顾性和前性审计.
- 对37名全甲状腺切除术后患者的激素替代疗法 (HRT) 的分析.
- 干预涉及对20名患者根据患者体重调整HRT.
主要成果:
- 调整后的THR剂量使所有患者群体的甲状腺激素和水平正常化.
- 在初始和调整后的THR组之间没有发现显著差异.
- 年龄较大,男性性别,BMI和手术前的TSH预测了激素治疗的需要.
结论:
- 基于体重的最佳THR对在甲状腺切除术后的甲状腺功能低下症中TSH水平产生积极影响.
- 根据既定的指导方针,THR处方应根据患者的体重标准化.
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