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Updated: Jul 8, 2025

A Method to Study de novo Formation of Chromatin Domains
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A Method to Study de novo Formation of Chromatin Domains

Published on: August 23, 2019

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H3K27me3扩散组织了正规的PRC1染色体架构,以调节发育程序

Brian Krug, Bo Hu, Haifen Chen

    bioRxiv : the preprint server for biology
    |December 20, 2023
    PubMed
    概括

    基因组H3K27三甲基化 (H3K27me3) 扩散控制多环,基因沉默和细胞命运. 异常的H3K27me3在质瘤中的限制通过维持原始状态来驱动瘤的发展.

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