慢性鼻炎中的病毒:系统性审查
Nitish Kumar1, Tripti Brar1, Hirohito Kita2
1Department of Otorhinolaryngology-Head & Neck Surgery, Mayo Clinic in Arizona, Phoenix, AZ, United States.
Frontiers in allergy
|December 20, 2023
概括
病毒在慢性鼻炎 (CRS) 患者中比对照患者更频繁地被发现,而鼻病毒是最常见的. 需要进一步的研究来澄清病毒在CRS发展和持久性中的确切作用.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 病毒学 病毒学
- 免疫学 免疫学 免疫学
背景情况:
- 病毒在慢性鼻炎 (CRS) 中的作用尚不清楚,与急性鼻炎不同.
- 病毒可能有助于启动,恶化或慢性炎症的CRS中鼻腔粘膜.
研究的目的:
- 系统地审查有关病毒在慢性鼻炎中的作用的文献.
- 描述病毒是否是CRS中鼻腔微生物组,殖民者或病原体的一部分.
主要方法:
- 使用Ovid Medline,Embase,Scopus和Web of Science数据库进行了对英语文学的系统审查.
- 搜索包括"病毒"",鼻炎"",犀利病毒"和"慢性鼻炎"等术语,更新至2023年9月.
主要成果:
- 30项研究符合纳入标准,分析了CRS中的病毒流行率,宿主易感性和病理途径.
- 病毒,特别是鼻病毒,在CRS受试者中比对照人群更为普遍.
- 病毒存在与鼻过敏反应,增加细菌易感性,免疫基因上调,呼吸道重塑和更糟糕的症状严重程度有关.
结论:
- 虽然病毒在CRS患者中似乎更普遍,但它们在CRS病理生理学中的确切作用尚不清楚.
- 需要进行大规模的纵向研究,采用标准化采样,以确定病毒在CRS中的作用.
更多相关视频
08:36Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
Published on: April 19, 2024
542
09:01An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
7.9K
相关概念视频
01:23Chronic Pharyngitis
2.3K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
2.3K
01:16Drugs Used in Upper Respiratory Disorders: Overview
254
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
254
01:30Acute Pharyngitis
703
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
703