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Updated: Jul 8, 2025

Mapping Genome-wide Accessible Chromatin in Primary Human T Lymphocytes by ATAC-Seq
09:08

Mapping Genome-wide Accessible Chromatin in Primary Human T Lymphocytes by ATAC-Seq

Published on: November 13, 2017

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表观基因组映射显示了不同的B细胞急性淋巴细胞白血病染色质结构和调节器

Kelly R Barnett1, Robert J Mobley1, Jonathan D Diedrich1

  • 1Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Cell genomics
|December 20, 2023
PubMed
概括

这项研究绘制了B细胞急性淋巴细胞白血病 (B-ALL) 的染色质可访问性,揭示了不同的TF驱动结构和遗传变异. 这些发现提供了关于B-ALL亚型和基因调节的见解.

关键词:
ATAC-QTLs的使用情况ATAC-seqq 的使用情况.急性淋巴细胞白血病急性淋巴细胞白血病染色质可访问性 染色质可访问性基因调节 基因调节 基因调节基因调节网络的基因调节网络.遗传变异是一种遗传变异.转录因子的转录因子转录因子的足迹

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