Oregano 精油调节肥牛的结肠平衡和肠道屏障功能
Yue Ma1, Jinping Shi1, Li Jia1
1College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.
Frontiers in microbiology
|December 20, 2023
概括
Oregano 精油 (OEO) 通过改变肠道微生物群和增加有益的代谢物来增强肥牛的肠道屏障功能. 这促进了胃肠道健康和动物福利.
科学领域:
- 动物科学 动物科学
- 微生物学 微生物学
- 胃肠病学 胃肠病学
背景情况:
- Oregano 精油 (OEO) 富含化合物,是肥牛的潜在食补充剂.
- 通过OEO影响牛肠道健康的分子机制尚不清楚.
- 了解OEO的影响对于通过植物产品改善动物福利和胃肠道健康至关重要.
研究的目的:
- 调查饮食中OEO补充剂对肥牛肠道屏障完整性的影响.
- 分析结肠微生物组合和微生物代谢物产生的变化.
- 阐明OEO对肠道健康和平衡的作用背后的分子机制.
主要方法:
- 在肥公牛中,用 Oregano 精油 (OEO) 补充食.
- 用于结肠微生物组分析的安普利康测序.
- 代谢组测序用于微生物代谢物分析.
- 对肠道屏障功能标记物的分析,包括基因表达和酶活性.
主要成果:
- OEO增加了结肠肌肉厚度,杯细胞数量,短链脂肪酸 (SCFA) 度和消化酶活性.
- OEO上调了与肠道屏障相关的基因和抗炎因子IL-10,同时降低了促炎细胞因子.
- OEO改变了肠道微生物群,增加了诸如*Bacteroides*和*Coprobacillus*之类的有益细菌,并修改了代谢物概况,包括增加了5-氨基瓦勒酸和降低了糖分.
结论:
- 饮食OEO补充剂改善了肥牛的肠道屏障完整性和功能.
- OEO调节结肠微生物群和代谢物生产,有助于更健康的肠道环境.
- 通过促进有益的微生物和抑制有害的微生物,OEO促进胃肠道平衡,支持动物福利.
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