通过生物芯片多阵列技术在牛奶样本中同时选六种类型抗生素残留物
Hassan Yazdanpanah1,2, Mahraz Osouli1, Jamshid Salamzadeh1
1Food Safety Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iranian journal of pharmaceutical research : IJPR
|December 20, 2023
概括
一种新的生物芯片方法有效地选牛奶中的六个抗生素家族,检测出低于欧洲限量的残留物. 这种快速技术确保了牛奶的安全性,并打击了抗菌素耐药性.
科学领域:
- 食品安全 食品安全
- 分析化学是一种分析化学.
- 兽医医学 兽医医学 兽医医学
背景情况:
- 在畜牧业中使用抗生素存在过敏反应和耐药性等风险.
- 牛奶中的抗生素残留物是一个重大的公共卫生问题.
- 目前的查方法可能耗时且昂贵.
研究的目的:
- 验证一种基于生物芯片的快速方法,用于同时对牛奶中的六个抗生素家族进行多分析查.
- 评估该方法是否符合欧盟委员会2002/657号决定和查指南.
- 确定生物芯片方法在现实环境中的适用性.
主要方法:
- 一种生物芯片测定方法的验证,用于检测诺,塞夫蒂奥弗,佛罗芬尼科尔,杆菌素,泰洛辛和四环素.
- 在单个牛奶样本中同时检测六个抗生素家族.
- 选来自伊朗伊朗共和国德黑兰省38个UHT母牛奶样本.
主要成果:
- 生物芯片方法显示出高灵敏度,阳性值高于Fm,CCβ低于欧洲最大残留量限值 (MRL).
- 在约8%的样本中检测到诺夫洛克萨,在2.63%的样本中检测到泰洛.
- 在测试的牛奶样本中,总体抗生素度低于已确定的MRL.
结论:
- 生物芯片技术是一种有效,快速和易于使用的方法,用于同时选牛奶中的六个关键抗生素家族.
- 该方法不需要样本准备,提高效率和降低成本.
- 这种经过验证的技术有助于确保牛奶的安全性和监测抗生素残留物.
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