改善了COPD患者使用tiotropium或tiotropium olodaterol与HealthPrize数字行为改变计划的药物坚持
Katrina S Firlik1, Vamshi Ruthwik Anupindi2, Vincent Hayes1
1HealthPrize Technologies, Norwalk, CT, USA.
Expert review of pharmacoeconomics & outcomes research
|December 20, 2023
概括
HealthPrize RespiPointsTM计划显著改善了慢性阻塞性肺病 (COPD) 的成年人药物坚持和持久性. 与非参与者相比,参与者表现出更好的坚持和减少药物停用.
科学领域:
- 肺部医学 肺部医学
- 健康 结果 研究 研究 结果
- 药物经济学 药物经济学
背景情况:
- 慢性阻塞性肺病 (COPD) 管理需要始终坚持药物治疗以获得最佳的患者结果.
- 对维护疗法如基 (TIO) 的低最佳坚持是COPD护理中的一个重大挑战.
- 数字健康计划旨在改善患者的参与度和对处方治疗的坚持.
研究的目的:
- 评估HealthPrize RespiPointsTM计划对成年COPD患者药物坚持和持续治疗的有效性.
- 为了比较计划参与者和非参与者之间的医疗保健资源利用率和相关成本.
主要方法:
- 这是一项回顾性队列研究,利用HealthPrize参与者的链接数据库和IQVIA PharMetrics® Plus数据.
- 使用倾向分数匹配 (PSM) 来创建可比的参与者和非参与者组,接受化 (TIO) 或TIO和olodaterol.
- 多变量逻辑回归分析了坚持 (覆盖日数比例 (PDC) ≥80%),中止风险和总医疗费用.
主要成果:
- 与非参与者 (n=262) 相比,计划参与者 (n=262) 的坚持率比非参与者 (n=262) 的坚持率高出44% (平均PDC为0.72比0.50,p<0.0001).
- 参与者具有显著更高的坚持率 (aOR 2.51,p<0.0001) 和较低的药物停用率 (19.85%与33.59%,p=0.0004).
- 调整后的医疗总费用对参与者来说下降了24% (p=0.08),尽管更高的药房费用部分抵消了这些节省.
结论:
- HealthPrize RespiPointsTM计划与改善了COPD成年人的药物坚持和持续性有关.
- 这些发现表明,数字依从计划可以积极影响COPD管理,并可能降低医疗保健成本.
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