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在SARS-CoV-2感染后,肺切除手术可以进行多长时间? 一个多中心的回顾性研究
Jiangnan Duan1, Ying Zhou2, Bengang Hui1
1Department of Thoracic Surgery.
International journal of surgery (London, England)
|December 20, 2023
概括
在严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 感染后,至少延迟肺切除4周,可显著减少术后并发症. 这一时间对于改善之前感染了SARS-CoV-2的患者的外科治疗结果至关重要.
科学领域:
- 胸部外科手术 胸部外科手术
- 传染性疾病 传染性疾病
- 肺部医学 肺部医学
背景情况:
- 没有先前的研究研究了SARS-CoV-2感染后肺切除的最佳时间.
- 这项研究通过分析手术结果和确定肺切除的理想感染后间隔来解决这一差距.
研究的目的:
- 评估SARS-CoV-2诊断和肺切除之间的时间间隔对术后并发症的影响.
- 确定肺切除的最佳时间,以尽量减少有SARS-CoV-2感染史的患者的手术风险.
主要方法:
- 一个多中心的回顾性队列研究,涉及400名接受肺切除的患者.
- 根据SARS-CoV-2诊断和手术之间的间隔对患者进行分组.
- 使用后勤回归分析来确定术后并发症的危险因素.
主要成果:
- 总共包括400名患者;80.5%患有肺癌. 随着SARS-CoV-2感染和手术之间的间隔增加,术后并发症率下降.
- 在SARS-CoV-2感染后4周内接受手术的患者的并发症率明显高于8周后接受手术的患者.
- 有关并发症的独立风险因素包括潜在疾病,持续的SARS-CoV-2症状和感染后4周内的手术.
结论:
- 肺切除应在SARS-CoV-2感染后至少推迟4周.
- 推迟手术可以显著降低患有SARS-CoV-2感染史的患者手术后并发症的风险.
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