探索血红色素和下肢静脉疾病之间的关联
Christina N Parker1, Kathleen J Finlayson, Emma J Hall
1In the School of Nursing, Queensland University of Technology, Queensland, Australia, Christina N. Parker, PhD, is Associate Professor; and Kathleen J. Finlayson, PhD, is Lecturer, Centre for Healthcare Transformation. Emma J. Hall, RN, is Clinical Nurse-Research Coordinator, Gold Coast Hospital and Health Service, Queensland, and Research Project Officer, Queensland University of Technology. Natasha Pitman, RN, is Registered Nurse, Infectious Diseases Unit, Princess Alexandra Hospital, Woolloongabba, Queensland. Wing Kei Chu, BMedLabSc, is Hematology and Blood Bank Scientist, QML Pathology, Murarrie, Queensland. Daniel F. Wallace, PhD, is Associate Professor, Queensland University of Technology. Acknowledgments: The authors acknowledge the valuable contribution of Tony Moorhead and Dianne Prince from Haemochromatosis Australia. The authors have disclosed no financial relationships related to this article. Submitted December 2, 2022; accepted in revised form February 3, 2023.
这项研究发现血红色素和慢性静脉疾病之间存在联系,血红色素患者的腿部的患病率更高. 需要进一步的研究来证实这一关联.
科学领域:
- 血管医学 血管医学
- 遗传学 遗传学 是一个
- 皮肤病学 皮肤病学
背景情况:
- 慢性静脉疾病 (CVD) 可以导致静脉腿部.
- 关于影响心血管疾病的基因变异的研究有限.
- 一些研究表明,血红色素和心血管疾病之间存在关联.
研究的目的:
- 审查文献,查看静脉疾病与血红色素病之间的关联.
- 调查血液染色症患者的静脉疾病和腿部的患病率.
主要方法:
- 进行了范围范围的系统文献审查.
- 一项横截面研究调查了患有血红色素病的个体.
主要成果:
- 文献综述发现了血染色体和静脉疾病/腿部之间的联系.
- 调查结果显示,在自我报告的血色素瘤患者中,腿部的患病率为9.2%,超过预期的比率.
- 血红色素病基因变异可能导致慢性静脉疾病和腿部的发展.
结论:
- 这项研究是首次对文献进行审查,并记录了血红色素和静脉腿部之间的关联.
- 研究中的重大缺口凸显了进一步调查的必要性.
- 目前仅有有限的证据来指导临床实践关于这种关联.
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