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成年人群的BMI轨迹与所有原因和特定原因死亡率相关:台湾的一项回顾性队列研究
Po-Wei Chiu1, Tsung Yu1, Shikha Kukreti1
1Department of Public Health, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
PloS one
|December 20, 2023
概括
了解身体质量指数 (BMI) 随着时间的推移而发生的变化对于死亡风险至关重要. 不同的BMI轨迹显示出与死亡率的不同关联,突出显示出根据年龄和性别需要个性化的健康干预措施.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 生物统计学 生物统计学
背景情况:
- 随着时间的推移,身体质量指数 (BMI) 的动态变化被认为是影响死亡风险的重要因素.
- 识别BMI变化 (轨迹) 的不同模式对于了解它们对健康结果的影响至关重要.
研究的目的:
- 根据身体质量指数 (BMI) 轨迹识别异质群体.
- 检查不同BMI轨迹与全因和因特定死亡风险之间的关联.
主要方法:
- 在台湾 (1998-2019年) 大规模前性队列上利用了基于组的轨迹分析.
- 将队列数据与国家死亡登记处联系起来,以获取死亡率信息.
- 采用Cox比例危险模型来评估BMI轨迹上的死亡风险 (危险比率),按年龄和性别分层.
主要成果:
- 确定了四个不同的身体质量指数 (BMI) 轨迹组.
- 在不同的BMI轨迹和死亡率之间展示了显著的关联.
- 观察到,肥胖可能会保护老年女性的癌症死亡率,而低正常体重会增加所有参与者的呼吸道死亡风险.
结论:
- 死亡风险在不同的BMI轨迹,年龄组和性别之间存在显著差异.
- 研究结果表明,针对特定的人口群体,量身定制的BMI建议和早期健康干预措施可以减轻死亡率.
- 突出了体重动态,特定死亡原因和人口因素之间的复杂关系.
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