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Updated: Jul 8, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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Published on: January 22, 2019

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JAK3 抑制剂抑制多效的 ILC2s,并减弱耐固醇喘的作用

Jihyun Kim1,2, Jongho Ham1,2,3, Hye Ryun Kang2,4

  • 1Laboratory of Mucosal Immunology, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.

Science advances
|December 20, 2023
PubMed
概括

第二组先天性淋巴细胞 (ILC2s) 可以在喘中对类固醇产生抗性,从而导致炎症. 用抑制剂准Janus激酶3 (JAK3) 提供了对抗类固醇喘的潜在治疗方法.

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