在R.E.N.A.L.之间存在关联 在脏瘤中,神经测量得分和生存结果
Xue Zhang1, Qi Sun2,3, Yangyang Qi4
1Department of Radiology, Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, China.
Japanese journal of clinical oncology
|December 20, 2023
概括
半径-外ophytic/内ophytic-近距离-前/后位置神经测量得分有效预测瘤的脏攻击性和患者的生存结果. 较高的分数表明风险更高,指导治疗决策以获得更好的预后.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 半径-外生/内生-接近-前/后位置神经测量得分 (RENAL得分) 用于手术规划和评估瘤的脏攻击性.
- 它与患者生存结果的直接关联需要进一步阐明.
研究的目的:
- 研究患有偶发性,单边性和非转移性瘤的患者的脏神经测量得分和生存结果之间的相关性.
- 根据RENAL得分复杂度,比较部分和彻底切除术之间的生存率.
主要方法:
- 在2009年1月至2019年9月期间,对1368名接受切除术的患者进行了回顾性分析.
- 三位泌尿科医生根据手术前的CT/MRI扫描进行了脏评分.
- 使用卡普兰-梅尔分析和多变量考克斯回归来评估生存结果和无复发生存期.
主要成果:
- 雷纳尔评分的所有组件都显示出与整体存活率和无复发存活率的显著关联 (大多数组件的P<0.001).
- 较高的RENAL分数复杂性组与明显较低的生存率有关 (P < 0.001).
- 雷纳尔评分是生存时间 (HR=1.151) 和无复发生存时间 (HR=1.299) 的独立不良预后因素. 部分切除术为RENAL分数为4和5的瘤提供了生存益处.
结论:
- 脏神经测量得分,包括其组件和复杂性组,与脏瘤患者的生存结果有显著的关联.
- 评分可以作为预测预后和指导外科治疗策略的宝贵工具.
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