滴滴大小分布在乳液中的分布
Manon L'Estimé1, Michael Schindler2, Noushine Shahidzadeh1
1Van der Waals-Zeeman Institute, Institute of Physics, University of Amsterdam, 1098XH Amsterdam, The Netherlands.
Langmuir : the ACS journal of surfaces and colloids
|December 20, 2023
概括
高剪切混合制造出具有日志正常滴粒大小分布的乳液,与流乳化理论不同. 在这个过程中,滴滴大小取决于毛细血管数,而不是雷诺兹数.
科学领域:
- 合体和表面科学科学
- 流体动力学 流体动力学
- 材料科学 材料科学 材料科学
背景情况:
- 乳液中的滴滴大小显著影响了质性质和应用性能.
- 在乳化过程中控制滴滴大小的机制尚未完全理解.
- 目前的乳化方法往往缺乏详细的机制理解.
研究的目的:
- 为了研究高剪切乳化过程中的平均滴滴大小和尺寸分布.
- 将高剪切乳化与流乳化理论模型进行比较.
- 在高剪切混合中确定控制滴滴大小的关键无维数.
主要方法:
- 使用高剪切混合机创建模型油入水乳液.
- 使用表面活性剂稳定了乳液.
- 分析了液滴大小分布和平均液滴大小.
主要成果:
- 滴滴大小分布遵循日志正常模式,归因于重复的随机滴滴断裂.
- 高剪切乳化结果与流乳化预测不同 (例如,科尔摩戈罗夫-欣泽理论).
- 用毛细血管数,而不是雷诺兹数缩放的平均滴滴大小,表明连续相位粘度至关重要.
结论:
- 高剪切乳化机制与流模型不同.
- 毛细管数是一个比雷诺兹数更相关的缩放参数,用于高剪切乳化.
- 了解这些机制对于控制各种应用中的乳液特性至关重要.
相关概念视频
Factors Affecting Dissolution: Particle Size and Effective Surface Area
851
Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
851
Precipitate Formation and Particle Size Control
783
In precipitation gravimetry, the precipitating agent should react specifically or selectively with the analyte. While a specific reagent reacts with the analyte alone, a selective reagent can react with a limited number of chemical species.
The obtained precipitate should be either a pure substance of known composition or easily converted to one by a simple process, such as ignition or drying. In addition, the precipitate should be insoluble and easily filterable. In general, filterability...
The obtained precipitate should be either a pure substance of known composition or easily converted to one by a simple process, such as ignition or drying. In addition, the precipitate should be insoluble and easily filterable. In general, filterability...
783


