紧急部门对COVID-19移植儿童的评估
Sagrario Barreiro Pérez1, Miguel Ángel Molina Gutiérrez2, Valeria Antoñanzas Bernar3
1Pediatric Department, La Paz University Hospital, P° Castellana, 261, 28046 Madrid, Spain.
The American journal of emergency medicine
|December 20, 2023
概括
儿科固体器官移植 (SOT) 和造血干细胞移植 (HSCT) 患者在感染SARS-CoV-2后通常经历了良好的结果. 大多数儿童出现发烧,住院发生在41.9%的儿童中,没有报告死亡.
科学领域:
- 儿科医学 儿科医学
- 传染性疾病 传染性疾病
- 移植手术 移植手术
背景情况:
- 儿童通常患有轻微的SARS-CoV-2 (COVID-19) 感染.
- 免疫功能低下的儿科患者,包括实体器官移植 (SOT) 和造血干细胞移植 (HSCT) 患者,可能表现出不同的疾病过程.
- 了解这些弱势儿科群体中COVID-19的表现非常重要.
研究的目的:
- 描述小儿SOT和HSCT接受者诊断出SARS-CoV-2的临床,实验室和放射学特征.
- 为了评估COVID-19在这个特定的儿科队列中的结果.
主要方法:
- 从2020年3月到2022年12月,在西班牙马德里进行了一项多中心回顾性观察研究.
- 包括儿童患者 (0-18岁) 与来自急诊室的SARS-CoV-2检测结果呈阳性.
- 收集的数据包括临床症状,实验室结果和放射学发现.
主要成果:
- 分析了31名小儿SOT/HSCT患者;只有一个无症状.
- 发烧是最常见的症状 (76.7%),12名患者有异常的胸部X射线 (66.6%).
- 医院住院发生在41.9%的患者中,没有死亡报告,无论移植类型或免疫抑制状态如何.
结论:
- 儿童SOT和HSCT患者的COVID-19的临床过程和结果通常是有利的.
- 这些发现强调了监测SARS-CoV-2在免疫受损儿童中的重要性.
- 进一步的研究可能会探索针对这一群体的特定管理策略.
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