相关实验视频

Updated: Aug 1, 2026

Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging
08:40

Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging

Published on: April 8, 2016

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探索以抗体为基础的近距离标记的雌激素受体近距离蛋白质的空间景观

Camilla Rega1, Zuzanna Kozik2, Lu Yu2

  • 1Division of Breast Cancer Research, The Institute of Cancer Research, London, United Kingdom.

Molecular & cellular proteomics : MCP
|December 20, 2023
PubMed
概括

这项研究引入了一种新方法,即通过抗体识别 (BAR) 进行生物化,用于绘制乳腺癌 (BC) 中雌激素受体α (ERα) 蛋白相互作用的地图. BAR揭示了ERα网络如何随着耐药性而改变,揭示了新的相互作用伙伴和机制.

关键词:
这里是巴巴巴巴巴巴巴巴巴巴巴巴.乳腺癌 乳腺癌 乳腺癌内分泌耐药性的内分泌抵抗.雌激素受体的受体是雌激素受体.质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量蛋白质相互作用 蛋白质相互作用接近性标签的标签.

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相关概念视频

Immunogold Electron Microscopy01:20

Immunogold Electron Microscopy

Immunoelectron microscopy utilizes immunogold labeling of endogenous proteins with specific antibodies to detect and localize these proteins in cells and tissues. The procedure provides insights into the distribution and quantification of protein under different stimulation conditions offering clues about their functions. Conjugating highly electron-dense gold particles with primary or secondary antibodies allow antigen detection on and within cells, with high resolution and specificity.