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Updated: Jul 7, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Published on: August 4, 2019

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无序的区域调解p53和MRE11的相互作用

Sinem Usluer1, Markus Galhuber2, Yukti Khanna1

  • 1Division of Molecular Biology and Biochemistry, Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Austria; Research Unit Integrative Structural Biology, Medical University of Graz, Austria.

Biochimica et biophysica acta. Molecular cell research
|December 20, 2023
PubMed
概括

这项研究揭示了p53和MRE11在DNA损伤部位的相互作用. 化和甲基化等翻译后修改调节了这一关键相互作用,影响了DNA修复和细胞反应.

关键词:
氨酸甲基化的阿尔金因.生物物理相互作用试验.本质上是无序的蛋白质.核磁共振光谱法 (NMR) 是一种光谱法.酸化是指酸化的方法.

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