带有结肠粘膜殖民化的子宫内膜异位症:一个诊断混者
Jeremy Adler1, Khaled Algashaamy2, Monica T Garcia de Buitrago3
1Kaiser Permanente, Oakland, California, USA.
Journal of clinical pathology
|December 20, 2023
概括
子宫内膜异位症可以扩散到结肠,有时会殖民结肠表皮. 这种罕见的现象可以模仿转移性癌症,需要仔细的病理审查.
科学领域:
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
- 妇科 妇科 妇科 妇科
背景情况:
- 子宫内膜异位症是一种良性疾病,其特点是子宫外的子宫内膜组织.
- 子宫内膜异位症的广泛传播可以模仿瘤过程.
- 远程癌细胞的二次粘膜殖民是已知的转移模式.
研究的目的:
- 描述和量化由子宫内膜异位症引起的结肠粘膜殖民的发生率.
- 评估子宫内膜异位症在胃肠道中模仿转移性疾病的潜力.
主要方法:
- 对38名患有子宫内膜异位症的胃肠道下部标本 (2016-2023) 的回顾性审查.
- 详细检查幻灯片以记录子宫内膜异位症的程度和位置.
- 专注于识别和表征由子宫内膜腺体的粘膜殖民.
主要成果:
- 子宫内膜异位症最常涉及远端结肠 (23例).
- 粘膜干扰发生在8例病例中 (21%),其中4例病例显示无上皮质殖民.
- 在2例粘膜干扰病例中,症状暗示恶性瘤 (质量或狭窄).
结论:
- 子宫内膜异位症偶尔会殖民结肠表皮 (10.5%的病例).
- 这种现象可以模仿转移性疾病或内皮质瘤.
- 它可以表现为一个误导性的模式,特别是当存在质量或狭窄时.
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