在老年人中绘制潜在不合适药物的地图,使用解剖治疗化学 (ATC) 分类系统
Asinamai Ndai1, Julie Al Bahou1, Earl Morris1
1Department of Pharmaceutical Outcomes & Policy, University of Florida College of Pharmacy, Gainesville, Florida, USA.
Journal of the American Geriatrics Society
|December 21, 2023
概括
在老年人中,潜在不合适的药物 (PIM) 被映射到解剖治疗化学 (ATC) 系统中. 这一步行人过道有助于在研究和临床实践中识别和协调PIM,88%的医疗保险受益者使用至少一个PIM.
科学领域:
- 老年人药理学 老年人药理学
- 药物安全 药物安全
- 医疗保健服务研究 医疗服务研究
背景情况:
- 可能不合适的药物 (PIMs) 对老年人构成风险,需要谨慎管理.
- 为了在这个群体中识别PIM,存在许多全球指南和工具.
- 需要采用统一的方法来增强PIM指导的临床和研究实用性.
研究的目的:
- 从八个主要指导方针/工具到解剖治疗化学物质 (ATC) 分类系统,开发一个行人交叉路口映射PIM.
- 为了利用这个步行者十字路口来比较跨指导方针的PIM,并估计老年人中的PIM流行率.
主要方法:
- 八个PIM指南/工具被映射到ATC5级 (药物) 和4级 (药物类别).
- 穿越路被用来识别参与处方级联 (指数和标记药物) 的PIM.
- 在医疗保险受益者中,使用描述性统计和数据可视化估计了PIM使用的流行程度.
主要成果:
- 在所有八个PIM指南中,只有三种特定药物和两种药物类别是共同的.
- 50%的索引药物类和47%的标记药物类在处方级联中被确定为PIM.
- 观察到PIM使用率很高,88%的医疗保险受益者至少使用了一种PIM.
结论:
- 成功创建了一条全面的行人交叉路口,将PIM指南与空中交通管制系统联系起来.
- 该工具有助于更容易地识别和协调用于研究和临床应用的PIM.
- 调查结果强调了老年人广泛使用PIM,强调了需要改进药物管理策略的需要.
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